VISDB Viral Integration Site DataBase

VIS ID

TVIS10013593

Fusion event

HBV-RAB2A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2393

Orient

+

Integrated sequence

CTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCG| |CAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCT

Chromosome

chr8

Cytoband

q12.2

Reference genome

Start

End

61519009/60606450 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-320a ; hsa-mir-142-3p ; hsa-mir-186-5p ; hsa-mir-765 ; hsa-mir-3174 ; hsa-mir-3150b-3p ; hsa-mir-4459 ; hsa-mir-4784 ; hsa-mir-6507-5p ; hsa-mir-6732-5p ; hsa-mir-6752-5p ; hsa-mir-6842-5p ; hsa-mir-6869-5p ; hsa-mir-7110-5p ; hsa-mir-4663 ; hsa-mir-4722-5p ; hsa-mir-4468 ; hsa-mir-6787-3p ; hsa-mir-1207-3p ; hsa-mir-4747-3p ; hsa-mir-6165 ; hsa-mir-3147 ; hsa-mir-6721-5p

Nearest miRNA

hsa-mir-124-1/Upstream/17710175; hsa-mir-10400/Downstream/1108338;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/88836, chr8-CpG: 127/Downstream/45195

Upstream sequence

ttcacagccgaattctaccagaggtacaaggaggagctggtaccattccttctgaaactattccaatcaatagaaaaagagggaatcctccctaactcat

Downstream sequence

TCTTACCTGAATTTATGCTGCCTATCTTGAACTAGGATCTTAAATTTAAAATGGCACCCAAGACAACACTTTGAAGTTTATTTCCAAAGAGCATAAGAAT