VISDB Viral Integration Site DataBase

VIS ID

TVIS10013596

Fusion event

HBV-TNKS integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2606

Orient

+

Integrated sequence

GTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCA| |CAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTA

Chromosome

chr8

Cytoband

p23.1

Reference genome

Start

End

9623236/9765726 (Hg38)

Orient

+

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-744-5p ; hsa-mir-324-3p ; hsa-mir-324-5p ; hsa-mir-142-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-4693-5p ; hsa-mir-3607-3p ; hsa-mir-1183 ; hsa-mir-1277-5p

Nearest miRNA

hsa-mir-3674/Upstream/23958; hsa-mir-10400/Downstream/137662;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/209143, chr8-CpG: 60/Downstream/132941

Upstream sequence

cctcccgagtagctgggattacaggtgcccgccacaatgtgtggctaatttcttgtatttttagtagagacagggtttcaccatgttgaccaggctggtc

Downstream sequence

GTTCTGCCACCGACAGAAGGAAGTGTCTGAGGAGAATCACAACCATCACAATGAGCGCATGTTGTTTCATGGTAAGCAGCGTGGCAGGGACGGTGGACGT