Basic Information
VIS ID
TVIS10013598
Fusion event
HBV-LINC01388 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
1930
Orient
+
Integrated sequence
CTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTG| |GAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGA
Host Sequence
Chromosome
chr9
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
111600/111600 (Hg38)
End
111600/111600 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC01388
Nearest miRNA
hsa-mir-1302-9/Upstream/81319; hsa-let-7a-1/Downstream/4738697;
Nearest TSS
ENST00000422679/Upstream/8659; ENST00000469197/Downstream/2154;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/37723, chr9-CpG: 211/Downstream/1316
Nearby gene
FAM138C(-75736) ; FOXD4(+4631) ;
Upstream sequence
cggagtttaggttacttcgtgtttaaacagtcttccagggaggggagtggggagggcaacccagtctttcatgtttcctcttcctcagcttgctgttccc
Downstream sequence
cgttcagtttctcccataaaaaatgcaagggaaacaaaaaaagaggattgaggaaatctaaaagagatataatagcccatatcaaccaaacacaatacgt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate