Basic Information
VIS ID
TVIS10013599
Fusion event
HBV-LINC01388 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1789
Orient
-
Integrated sequence
GACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGG| |CATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGG
Host Sequence
Chromosome
chr9
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
111628/111628 (Hg38)
End
111628/111628 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC01388
Nearest miRNA
hsa-mir-1302-9/Upstream/81347; hsa-let-7a-1/Downstream/4738669;
Nearest TSS
ENST00000422679/Upstream/8687; ENST00000469197/Downstream/2126;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/37751, chr9-CpG: 211/Downstream/1288
Nearby gene
FAM138C(-75764) ; FOXD4(+4603) ;
Upstream sequence
AGAAAAGTGAAAAAATGGTGAGATTTTACTTCAAAAAATCCAAATTATATGCAACTTAAGTCATCTTCAGTAGAGTTTCAGAAATGATAGGGGAGATACA
Downstream sequence
gggaaacaaaaaaagaggattgaggaaatctaaaagagatataatagcccatatcaaccaaacacaatacgtaacccttattagcattctaattcaaacc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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