Basic Information
VIS ID
TVIS10013602
Fusion event
HBV-LOC107987077 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1789
Orient
-
Integrated sequence
GACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGG| |CATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGG
Host Sequence
Chromosome
chr9
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
70924450/68309534 (Hg38)
End
70924450/68309534 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107987077
Nearest miRNA
hsa-mir-101-2/Upstream/27075699; hsa-let-7a-1/Downstream/2500441;
Nearest TSS
ENST00000422679/Upstream/2141; ENST00000429953/Downstream/12877;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1727, chr9-CpG: 96/Downstream/47099
Nearby gene
FOXD4L3(-4450) ; PGM5-AS1(+45659) ;
Upstream sequence
ctgcaagtggatatttggatagctttgaggatttcattggaaacaggaatatcttcatataaaatctagacagaagcattctcagaaacatctctgtgat
Downstream sequence
gcattttttatgggagaaactgaactgtttgttctgaagaagttgacattctgaactttgTAGCTGCAGGTAATAGTTTTTTGGCAAGATATTCCCAGGG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate