Basic Information
VIS ID
TVIS10013605
Fusion event
HBV-chrX integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|
Start
1875
Orient
+
Integrated sequence
TAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCC| |AAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTC
Host Sequence
Chromosome
chrX
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
92041601/92786602 (Hg38)
End
92041601/92786602 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/6882895; hsa-mir-105-1/Downstream/2276539;
Nearest TSS
ENST00000429181/Upstream/951097; ENST00000332647/Downstream/886966;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1004332, chrX-CpG: 20/Downstream/886945
Nearby gene
PCDH11X(-163373) ; NAP1L3(+884324) ;
Upstream sequence
caaggcgggcagatcacgaggtcaggagttcaagaccagcctgaccaacatggtgaaaccccgtctctactaaaaatacaaaaattagctggggcatggt
Downstream sequence
tagaaagtaagtggagaaatgcaccctctctctatatatatatgggtattgcttatgaaaaagctaatcaaaggtatgcccatgtgcaggtggggtgaca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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