Basic Information
VIS ID
TVIS10013606
Fusion event
HBV-chrX integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1688
Orient
-
Integrated sequence
CGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAA| |CGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAG
Host Sequence
Chromosome
chrX
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
92044496/92789497 (Hg38)
End
92044496/92789497 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7f-2/Upstream/6885790; hsa-mir-105-1/Downstream/2273644;
Nearest TSS
ENST00000429181/Upstream/953992; ENST00000332647/Downstream/884071;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/1007227, chrX-CpG: 20/Downstream/884050
Nearby gene
PCDH11X(-166268) ; NAP1L3(+881429) ;
Upstream sequence
gttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggtta
Downstream sequence
TGAGGTAGAATTTCATTTTTGCtcagtttctctagtaggtgcacgataattcaaactatctatgttttattttcagtcagttttatatatgacattttaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate