Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013616
Fusion event
HBV-SYTL2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1707
Orient
-
Integrated sequence
GCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATA| |CTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCA
Host Sequence
Chromosome
chr11
Cytoband
q14.1
Reference genome
Start
End
85467604/85756561 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10392/Upstream/3865725; hsa-let-7a-2/Downstream/521772;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/91371, chr11-CpG: 40/Downstream/54406
Upstream sequence
GTTAACAAATGAGTACCTaagactgggatttgattctcacttctgacacctaccagttgtgtgatattgggcgagtcacctgacttgtctcaaagtcaac
Downstream sequence
ttcctgacacatcaaatggggtaattatatcccactccacccaccaaccgcaaaagagtatgtgagctcataaaaaataatgggcatgttaagccctttg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.