VISDB Viral Integration Site DataBase

VIS ID

TVIS10013638

Fusion event

HBV-GFOD2 integration

Validated

Yes

Detection method

PCR and Sanger sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1041

Orient

-

Integrated sequence

GAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTG| |GTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAA

Chromosome

chr16

Cytoband

q22.1

Reference genome

Start

End

67709426/67675523 (Hg38)

Orient

+

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-421

Nearest miRNA

hsa-mir-1225/Upstream/473128; hsa-mir-11401/Downstream/557903;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/8072, chr16-CpG: 60/Downstream/43423

Upstream sequence

GGGGCCCCTGCTCAGGCAGTCCTGCGCCCACTGCCAGCGAGTCCCTCAAGAGCAGCTCCTCTTGCGTGGCAGAGTTCTTCTGCCCATAGAGGTCGGCTCC

Downstream sequence

CCGGGCGACGAGGCGTCCTGCAGAGCCTACCACCATGACTTCATGCACAAAGGCGCCTGGCATGTTGAAGTTGAGTGTCACTGTGCTACACACACCCCCA