Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013653
Fusion event
HBV-ZNF804B integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|large S protein|
Start
2876
Orient
+
Integrated sequence
TTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAAT| |CCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAG
Host Sequence
Chromosome
chr7
Cytoband
q21.13
Reference genome
Start
End
88909218/89279904 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10525/Upstream/13364635; hsa-mir-10399/Downstream/2924111;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/519935, chr7-CpG: 98/Downstream/838674
Upstream sequence
tgggaaaccggtgaagggtgtgaagctgggggtgatgacccgTGAAGCCCGAGGCTGCAACACAAGGGGAGAGCTGTCCAAAGGTTCGCCAAATTCTggc
Downstream sequence
gacctaatagacatctacagaactctccaccccaaatcaacagaatatacatttttttcaacaccacaccacacctattccaaaattgaccacatagttg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.