Fusion event
HBV-chr1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
Polymerase|large S protein|middle S protein|
Integrated sequence
GTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTG| |GGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAAT
End
88055504/87589821 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/1232134; hsa-mir-11399/Downstream/6257011;
Upstream sequence
GTGTTATCTTTGTCACTGCTGCAGAAAAATGCAGAAAAGAGCCCTAACTATGACAGCACAAGGGTGCTGTTGAACAACCAGTATAGGAGAGAGGCTGGAG
Downstream sequence
TCTGCACCGTGACAGGCATTGGCTTATGGAGCAAAGGATCGGTGATGCCTTAGGAAAGGGACAGTGTAGTCTGGGCAGGAGAAGCCTTGGGGAATCAGGG
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.