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Viral Integration Site DataBase
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TVIS10013664
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013664
Fusion event
HBV-ALG9 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
S protein|Polymerase|large S protein|middle S protein|
Start
325
Orient
+
Integrated sequence
AGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAA| |CCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATG
Host Sequence
Chromosome
chr11
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
111659737/111789013 (Hg38)
End
111659737/111789013 (Hg38)
Orient
+
Location type
Intronic
Target gene
ALG9
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-513a-5p
;
hsa-mir-130b-5p
;
hsa-mir-380-3p
;
hsa-mir-411-3p
;
hsa-mir-4495
;
hsa-mir-379-3p
;
hsa-mir-30e-5p
;
hsa-mir-30c-5p
;
hsa-mir-30b-5p
;
hsa-mir-30a-5p
;
hsa-mir-30d-5p
;
hsa-mir-27a-3p
;
hsa-mir-27b-3p
;
hsa-mir-4266
;
hsa-mir-4779
;
hsa-mir-4695-5p
;
hsa-mir-6753-5p
;
hsa-mir-1911-3p
;
hsa-mir-513c-3p
;
hsa-mir-513a-3p
;
hsa-mir-3606-3p
;
hsa-mir-1273e
;
hsa-mir-4722-5p
;
hsa-mir-4524a-3p
;
hsa-mir-6746-5p
;
hsa-mir-1247-3p
;
hsa-mir-4768-3p
;
hsa-mir-6165
;
hsa-mir-302f
;
hsa-mir-4772-5p
;
hsa-mir-5590-3p
;
hsa-mir-873-5p
;
hsa-mir-142-5p
;
hsa-mir-624-3p
;
hsa-mir-548l
;
hsa-mir-8054
;
hsa-mir-548k
;
hsa-mir-548av-5p
;
hsa-mir-559
;
hsa-mir-548y
;
hsa-mir-548w
;
hsa-mir-548o-5p
;
hsa-mir-548j-5p
;
hsa-mir-548i
;
hsa-mir-548h-5p
;
hsa-mir-548d-5p
;
hsa-mir-548c-5p
;
hsa-mir-548bb-5p
;
hsa-mir-548b-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548au-5p
;
hsa-mir-548as-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548am-5p
;
hsa-mir-548ak
;
hsa-mir-548ae-5p
;
hsa-mir-548ad-5p
;
hsa-mir-548ab
;
hsa-mir-548a-5p
;
hsa-mir-7-5p
;
hsa-mir-3611
;
hsa-mir-4693-5p
;
hsa-mir-3185
;
hsa-mir-4512
;
hsa-mir-4773
;
hsa-mir-4318
;
hsa-mir-892a
;
hsa-mir-7703
;
hsa-mir-6729-5p
;
hsa-mir-4649-5p
;
hsa-mir-4252
;
hsa-mir-4793-3p
;
hsa-mir-1292-3p
;
hsa-mir-338-3p
;
hsa-mir-4530
;
hsa-mir-1273g-3p
;
hsa-mir-508-5p
;
hsa-mir-6070
;
hsa-mir-5195-3p
;
hsa-mir-145-5p
;
hsa-mir-4267
;
hsa-mir-5588-3p
;
hsa-mir-1273a
;
hsa-mir-766-3p
;
hsa-mir-7977
;
hsa-mir-23b-5p
;
hsa-mir-23a-5p
;
hsa-mir-376a-5p
;
hsa-mir-4766-5p
;
hsa-mir-4793-5p
;
hsa-mir-5196-3p
;
hsa-mir-3121-3p
;
hsa-mir-3160-3p
;
hsa-mir-377-5p
;
hsa-mir-4257
;
hsa-mir-431-3p
;
hsa-mir-4487
;
hsa-mir-455-3p
;
hsa-mir-558
;
hsa-mir-6086
;
hsa-mir-6499-3p
;
hsa-mir-6516-5p
;
hsa-mir-7160-5p
;
hsa-mir-7162-3p
Nearest miRNA
hsa-mir-10392/Upstream/275498; hsa-let-7a-2/Downstream/1661010;
Nearest TSS
ENST00000527297/Upstream/10663;
ENST00000530799/Downstream/20677;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/22523
,
chr11-CpG: 47/Downstream/89833
Upstream sequence
AGCTTCATTAATATAGTCATTGTATATTTCTGGTCAACTCAGTccttagtataacctcagggtccagtggacccaattttagttttcaactttctttttt
Downstream sequence
ttttttcccccaagagacagggtctcactattttgcccaggctggccttgaactcctgggctcaagcaatcctcctgcctcggtctcccaaactgttggg
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Sample Information
×
Sample name
828P
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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