Basic Information
VIS ID
TVIS10013667
Fusion event
HBV-LINC02712 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2483
Orient
-
Integrated sequence
CCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACT| |TTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATG
Host Sequence
Chromosome
chr11
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
127179568/127309673 (Hg38)
End
127179568/127309673 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02712
Nearest miRNA
hsa-let-7a-2/Upstream/321131; hsa-mir-4697/Downstream/1212717;
Nearest TSS
ENST00000527297/Upstream/38611; ENST00000609911/Downstream/870754;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/305759, chr11-CpG: 20/Downstream/1142093
Nearby gene
KIRREL3-AS3(-303615) ; ETS1(+1149088) ;
Upstream sequence
aggtaacatttatttgagaaaaccagatgtaaggacaggggaagtcttctgaaaaaaagaaacaggtctaagcaacttaaattcaggtatatatgagatt
Downstream sequence
aagttcataaagaattgatgggcattgagaatcttctggtggcagtgatggcttaggcaagtttaggaacatatatgtctactgcacttaattttaaaat
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate