VISDB Viral Integration Site DataBase

VIS ID

TVIS10013668

Fusion event

HBV-C11orf58 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1218

Orient

-

Integrated sequence

TTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGCAACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGG| |TCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGC

Chromosome

chr11

Cytoband

p15.2

Reference genome

Start

End

16765955/16744408 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA11C ; FRA11I

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-mir-769-3p ; hsa-mir-504-5p ; hsa-mir-488-3p ; hsa-mir-1183 ; hsa-mir-1278 ; hsa-mir-1911-5p ; hsa-mir-4742-3p ; hsa-mir-4517 ; hsa-mir-6869-5p ; hsa-mir-6730-5p ; hsa-mir-5681a ; hsa-mir-1322 ; hsa-mir-5583-3p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6748-5p ; hsa-mir-6769b-5p ; hsa-mir-6769a-5p ; hsa-mir-3165 ; hsa-mir-4483 ; hsa-mir-1293 ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-6745 ; hsa-mir-363-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4768-3p ; hsa-mir-4761-5p

Nearest miRNA

hsa-mir-210/Upstream/774787; hsa-let-7a-2/Downstream/1643379;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/5569, chr11-CpG: 93/Downstream/180437

Upstream sequence

gggctgtagccctgcagtctgttttaacaagccctctaggtgacgctgatagaggcaaacttttgagaCTCAGCTCTGGCTGTAGGAGAACTAAAGGATT

Downstream sequence

CTGCTGTGAGGTAATAGAAAAGGAGTAAATTTGAATGTGATGAATATGCTTAACTTCCTAAGCAAGAAAAATGAACGCTGTTTATAGTTACAACTGACAG