Fusion event
HBV-chr12 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
X protein|precore/core protein|
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
End
105636638/105242860 (Hg38)
Nearest miRNA
hsa-let-7i/Upstream/651144; hsa-mir-1178/Downstream/3392950;
Upstream sequence
TGTGGTCAATGAAattcagttctatgcatattaatgaagcatgtactttgttccaagcaccgaggtaggcactgcaggtttaataacgtaaaagaaacat
Downstream sequence
ggacttgctgcccttcaagggagattcccatctactaatggcagacgattaaaaacaGGAGTGTTCCAGTAGAGGACAATCCACATGACACAGGGAGCAC
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.