CATSPERB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013675
Fusion event
HBV-CATSPERB integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1689
Orient
+
Integrated sequence
GCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAAC| |GACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGG
Host Sequence
Chromosome
chr14
Cytoband
q32.12
Reference genome
GRCh37/hg19
Start
92060712/91594368 (Hg38)
End
92060712/91594368 (Hg38)
Orient
-
Location type
Intronic
Target gene
CATSPERB
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-23b-3p
Nearest miRNA
hsa-mir-1260a/Upstream/14328078; hsa-mir-1185-1/Downstream/2353858;
Nearest TSS
ENST00000550708/Upstream/1816; ENST00000553427/Downstream/51867;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/19836, chr14-CpG: 57/Downstream/241489
Upstream sequence
ttgaacaatgagaacacatggacacaggaaggggaacatcacacaccagggactgttgtggggtggggggatgggggagggatagcattaggagatatac
Downstream sequence
ctaatgctaaatgacgagttaatgggtgcagcacaccaacatggcacatgtatacatatgtgacaaacctgcacgttgtgcacatgtaccctaaaactta
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate