VISDB Viral Integration Site DataBase

VIS ID

TVIS10013681

Fusion event

HBV-ZNF606 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1733

Orient

-

Integrated sequence

CAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACT| |GGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTC

Chromosome

chr19

Cytoband

q13.43

Reference genome

Start

End

58490782/57979414 (Hg38)

Orient

+

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-103a-3p ; hsa-let-7b-5p ; hsa-mir-653-3p ; hsa-mir-5192 ; hsa-mir-4306 ; hsa-mir-4644 ; hsa-mir-185-5p ; hsa-mir-107 ; hsa-mir-1827 ; hsa-mir-3163 ; hsa-mir-34b-3p ; hsa-mir-522-3p ; hsa-mir-224-3p ; hsa-mir-3662

Nearest miRNA

hsa-let-7e/Upstream/2591172; hsa-mir-10394/Downstream/355274;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/31563, chr19-CpG: 110/Downstream/22673

Upstream sequence

GGGTTTTATTCCAGTGTGAGTCCGTTCATGTTTCGTAAGGGCTGAGCGATTCCTAAAAACTTTTCCACATTTATCACATTCATAGGGTTTTTCTCCAGTA

Downstream sequence

TGAGTTTTCTTATGTTGAATAAGGTAAGAGCTCCAGATGAAAGACGTCCCACATTCATTGTAGTCATAGGGTTTCTCTGCAGTGTAAGTGCTTGTATGTT