Fusion event
HBV-FN1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
Polymerase|large S protein|
Integrated sequence
CATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGG| |ATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGG
End
216269485/215404762 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10b/Upstream/1646603; hsa-mir-1244-1/Downstream/2495751;
Upstream sequence
AAAAGATGAAACATGCCAAGAAATATTTAGATCAGTAATGATCATAACTCAAGTCCTGAAACTTGATTGAATGTCTAAGTTTTCTCTCCTCAAGGTTGTA
Downstream sequence
ACTATGTGAAAGTCAAAACCCTGGAAAAACTGAGCCAGTAAGAGATTGAGTGCTACACAAAACTTTGCCAAAACTCTGCCAGTCATGAGAAATTGTGGAA
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.