VISDB Viral Integration Site DataBase

VIS ID

TVIS10013692

Fusion event

HBV-NEDD9 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

2842

Orient

+

Integrated sequence

ACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGAT| |CTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGAT

Chromosome

chr6

Cytoband

p24.2

Reference genome

Start

End

11350155/11349922 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-18a-5p ; hsa-mir-145-5p ; hsa-mir-30c-5p ; hsa-mir-218-5p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-642a-5p ; hsa-mir-4477a ; hsa-mir-5682 ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-5702 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6871-3p ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-4506 ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-3912-3p

Nearest miRNA

hsa-mir-3691/Upstream/910128; hsa-mir-10398/Downstream/4791634;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/255488, chr6-CpG: 182/Downstream/187382

Nearest cancer related gene

NEDD9(OG, No orient, 0)

Upstream sequence

ggtttcaccgtggtggccaggatggtctccgtctcctgacctcgtgatccgcctgcctctgcctcccaaagcgctgggattacaggcgtgagccaccgtg

Downstream sequence

aaagttaaaaaaataaTCCTTGGCCTATCTAGCTTAGAGAGGCTCTTAGTTTGAAAGAGACAATGGATGGTGTGCAAATTGAAGGTCACATTATCCTTCT