Fusion event
HBV-chr12 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
precore/core protein|Core and e antigen|
Integrated sequence
ACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCT| |AGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAG
End
61479459/61085678 (Hg38)
Nearest miRNA
hsa-mir-1228/Upstream/3260986; hsa-let-7i/Downstream/1174681;
Upstream sequence
aatttgtgtttgtcaatcatacctcagtaaagctggaaaaaTTAATGTAAAATACATTTTTAAAAAAGGAAGATAAAAGAGAAGTCCAGAGTGAGGATCA
Downstream sequence
CATTATTCTTTGTTTATAAGAAAAAATTAGCATAAATCAGAAAATGTTTATTGTTAAATTAAATTCAATGAAAGCAAGATTTTTTATGCATCTTAGTAAT
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.