KIAA1217 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013713
Fusion event
HBV-KIAA1217 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1624
Orient
+
Integrated sequence
GGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTG| |AACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGT
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
24792721/24503792 (Hg38)
End
24792721/24503792 (Hg38)
Orient
-
Location type
Intronic
Target gene
KIAA1217
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-4286 ; hsa-mir-6507-3p
Nearest miRNA
hsa-mir-1265/Upstream/228011; hsa-mir-107/Downstream/3785466;
Nearest TSS
ENST00000439456/Upstream/8818; ENST00000492009/Downstream/29420;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/807743, chr10-CpG: 209/Downstream/218876
Upstream sequence
aaaactaattactgagtactctgcaggccaaaggacacaattgcagttcagagggggcctatcggctcccaagttcgTTCTTACCTGGGGCTCCTGGAGG
Downstream sequence
TCAAGCCCTTCCCTTCACTGCTCCTGCCTTTTGGCACCATCTGCTGGCCATTTCGAAATTGTTACCTCCTCATTGCGCCCTTTAAGAAAAACATACATAT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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