VISDB Viral Integration Site DataBase

VIS ID

TVIS10013714

Fusion event

HBV-MYO3A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1873

Orient

+

Integrated sequence

ACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCT| |CCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTT

Chromosome

chr10

Cytoband

p12.1

Reference genome

Start

End

26354198/26065269 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-409-3p ; hsa-mir-6894-3p ; hsa-mir-4276 ; hsa-mir-3127-5p ; hsa-mir-550a-5p ; hsa-mir-550a-3-5p ; hsa-mir-1271-3p ; hsa-mir-138-5p ; hsa-mir-6131 ; hsa-mir-133a-5p ; hsa-mir-4763-5p ; hsa-mir-3692-5p ; hsa-mir-6893-3p ; hsa-mir-370-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-3918 ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p

Nearest miRNA

hsa-mir-1265/Upstream/1789488; hsa-mir-107/Downstream/2223989;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/130176, chr10-CpG: 40/Downstream/146409

Upstream sequence

gcgcctggtagattaggtaaaatgaggacttaaaattgaccattggatttagcaatgtaaaggtcaatagagtccttaacaaaagctgcttccacagagt

Downstream sequence

gtcaagatgaaagcctgaagaaactaagtatatgccgagcatggtggctcacgcctataatccaagcacactgggaggccaaagtgggcagatcacttga