Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013726
Fusion event
HBV-CNTN5 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1859
Orient
+
Integrated sequence
TTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCC| |TACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTG
Host Sequence
Chromosome
chr11
Cytoband
q22.1
Reference genome
Start
End
99868384/99997652 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10392/Upstream/3656126; hsa-let-7a-2/Downstream/1522168;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/976561, chr11-CpG: 64/Downstream/689540
Upstream sequence
cacagccgaattctaccagaggtacaaggaggaactggtaccatttcttctgaaattattccaatcaatagaaaaagagggaatcctccctaactcactt
Downstream sequence
tatgaggccagcatcatcctgagaccaaagccgggcagagacacaaccaacaaagacaattttagaccaatatccttgatgaacattgatgcaaaaatcc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.