Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013750
Fusion event
HBV-ALOX12P2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1859
Orient
+
Integrated sequence
TTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCC| |TACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTG
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
Start
End
6789224/6885905 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
Nearest miRNA
hsa-mir-1253/Upstream/230396; hsa-mir-10226/Downstream/131710;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/109514, chr17-CpG: 21/Downstream/8205
Upstream sequence
tgcattgatgttcatcagggatattggtattaaattctcttttttttttgttgtgtctctgccaggctttggtatcaggatgatgctggcctcataaaat
Downstream sequence
gagttagggaggattccctctttttctattgattggaatcgtttcagaaggaatggtaccagctcctccttgtacctctggtagaattcggctgtgaatc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.