Basic Information
VIS ID
TVIS10013755
Fusion event
HBV-LOC101927151 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
precore/core protein|Core and e antigen|
Start
1962
Orient
+
Integrated sequence
TGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCT| |TCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTG
Host Sequence
Chromosome
chr19
Cytoband
q11
Reference genome
GRCh37/hg19
Start
28355957/27865049 (Hg38)
End
28355957/27865049 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC101927151
Nearest miRNA
hsa-mir-10395/Upstream/7465695; hsa-let-7e/Downstream/7257651;
Nearest TSS
ENST00000633603/Upstream/71000; ENST00000586671/Downstream/24173;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/58854, chr19-CpG: 45/Downstream/44323
Nearby gene
LINC00662(-71109) ; LINC00906(+1100081) ;
Upstream sequence
tattggtctaaaattctcttttttggttgtgtctctgccaggctttggtatcaggatgatgctggcctcacagcatgagttaaggatgattccctctttt
Downstream sequence
tctattgattggaatagtttcagaaggaatggtaccagctcctccttgtacctctggtagaattcggctgtgaatccgtctggtcctggactttttttga
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate