VISDB Viral Integration Site DataBase

VIS ID

TVIS10013760

Fusion event

HBV-FBXO36 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1859

Orient

+

Integrated sequence

TTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCC| |TACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTG

Chromosome

chr2

Cytoband

q36.3

Reference genome

Start

End

230832612/229967896 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-6079 ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-671-5p ; hsa-mir-6828-5p ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-4786-3p ; hsa-mir-383-3p ; hsa-mir-3677-5p

Nearest miRNA

hsa-mir-10b/Upstream/2495709; hsa-mir-1244-1/Downstream/1394812;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/44947, chr2-CpG: 96/Downstream/99856

Upstream sequence

ttttgcattgatgttcatcagggatatttgtctaaaattctctttttttgttgtgtctctgcccggctttggtatcaggatgatgctggcctcgtaaaat

Downstream sequence

gagttagggaggattccctctttttctattgattgtaatagtttcagaaggaatggtaccagctcctccttgtacctctggtagaattcggctgtgaatc