VISDB Viral Integration Site DataBase

VIS ID

TVIS10013775

Fusion event

HBV-GSTCD integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|

Start

1895

Orient

+

Integrated sequence

TTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT| |TTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTA

Chromosome

chr4

Cytoband

q24

Reference genome

Start

End

106653395/105732238 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-132-3p ; hsa-mir-4668-5p ; hsa-mir-4804-3p ; hsa-mir-3613-3p ; hsa-mir-5583-5p ; hsa-mir-3129-3p ; hsa-mir-129-5p ; hsa-mir-7850-5p ; hsa-mir-5004-3p ; hsa-mir-6749-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-532-3p ; hsa-mir-1224-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-6513-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-665 ; hsa-mir-3678-3p ; hsa-mir-6771-5p ; hsa-mir-7160-5p ; hsa-mir-4722-5p ; hsa-mir-2467-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6746-5p ; hsa-mir-4768-3p ; hsa-mir-4257 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-500a-5p ; hsa-mir-6086 ; hsa-mir-377-5p

Nearest miRNA

hsa-mir-12113/Upstream/4401824; hsa-mir-1243/Downstream/3756460;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/23181, chr4-CpG: 136/Downstream/163020

Upstream sequence

catagcaagaccctggttcaaaaaaaaaaaattagacaggtgaggtggtgcatgtctgtagttctagcttcttgggaggctaaggtgggaaggtttcttg

Downstream sequence

ttgattggaatagtttcagaaggaatggtaccagctcctccttgtacctctggtagaattcggctgtgaatccgtctggtcctggactttttttggttgg