VISDB Viral Integration Site DataBase

VIS ID

TVIS10013787

Fusion event

HBV-FYB1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2063

Orient

+

Integrated sequence

CTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGC| |ACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGT

Chromosome

chr5

Cytoband

p13.1

Reference genome

Start

End

39244788/39244686 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-4795-3p ; hsa-mir-613 ; hsa-mir-206 ; hsa-mir-1-3p ; hsa-mir-126-5p ; hsa-mir-4307 ; hsa-mir-656-3p ; hsa-mir-33a-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p

Nearest miRNA

hsa-mir-10397/Upstream/687125; hsa-mir-103a-1/Downstream/14706818;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/169552, chr5-CpG: 39/Downstream/180104

Upstream sequence

ATTTCATGTAAGGATAAGGAAGTGATCATTTAATCATTAGGCATGACAAAGCAAGCATGCTAGATTTGGCCAAAATGTAATTATATACAATGTCAGTTGC

Downstream sequence

attgattggaatagtttcagaaggaatggtaccagctcctccttgtacctctggtagaattcggctgtgaatccgtctggtcctggactttttttggttg