Basic Information
VIS ID
TVIS10013814
Fusion event
HBV-PIR-FIGF integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|precore/core protein|
Start
1835
Orient
+
Integrated sequence
GAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTG| |CCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCT
Host Sequence
Chromosome
chrX
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
15432249/15414127 (Hg38)
End
15432249/15414127 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
PIR-FIGF
Nearest miRNA
hsa-mir-3690-1/Upstream/1823781; hsa-let-7f-2/Downstream/1212885;
Nearest TSS
ENST00000429181/Upstream/6474; ENST00000463891/Downstream/50119;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/78241, chrX-CpG: 35/Downstream/79061
Upstream sequence
agcaccacaccacagctattccaaaattgaccacatagttggaagtaaagctctcctcagcaaatgtaaaagaacagaaattataacaaactatctctca
Downstream sequence
TGATTATTTTCTTGCTAATACAATAGTACTACAAATGTATTAGAATGCCCTAGAAGCTTATTAGAATGCCCTAGAAGCTTATCCTGTTCTTTAAAAAAAG
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate