Basic Information
VIS ID
TVIS10013823
Fusion event
HBV-chrY integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
precore/core protein|
Start
1859
Orient
+
Integrated sequence
TTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCC| |TACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTG
Host Sequence
Chromosome
chrY
Cytoband
p11.2
Reference genome
End
9947087/10109478 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3690-2/Upstream/5503250; hsa-mir-12120/Downstream/3369699;
Nearby gene
TTTY23(-197516) ;
Upstream sequence
gggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggtgagggttagggttagggttagggttagggt
Downstream sequence
gtgagttagggaggattccctctttttctattgattggaatagtttcagaaggaatggtaataactcctccttgtacctctggtagaattcggctgtgaa
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate