VISDB Viral Integration Site DataBase

VIS ID

TVIS10013824

Fusion event

HBV-ST7L integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

532

Orient

-

Integrated sequence

TTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGA| |CTACTGCTCAAGGAACCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGG

Chromosome

chr1

Cytoband

p13.2

Reference genome

Start

End

113108327/112565705 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-mir-18a-3p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-7154-3p ; hsa-mir-7106-5p ; hsa-mir-4731-5p ; hsa-mir-7515 ; hsa-mir-7113-5p ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4756-5p ; hsa-mir-4270 ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-23a-3p

Nearest miRNA

hsa-mir-101-1/Upstream/103872; hsa-mir-11399/Downstream/316345;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/56026, chr1-CpG: 76/Downstream/53264

Upstream sequence

ACTGTTTTCAAAATCTTCACCACTACCTCATCTCAACAAAGGAATCCCCCAAACCTTATACATTCTAAGGCTACAAACACTAAAATAACATCCACAAAGA

Downstream sequence

AACAAACACTGAACAACTCAAAGAAGATGggccaggcacagtggctcatgcctgtaatcccagcactttgggaggccaaggtgggcggactgcttgagcc