VISDB Viral Integration Site DataBase

VIS ID

TVIS10013827

Fusion event

HBV-KCNN3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1807

Orient

-

Integrated sequence

CTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCA| |CCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGA

Chromosome

chr1

Cytoband

q21.3

Reference genome

Start

End

154814159/154841683 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-889-3p ; hsa-mir-155-5p ; hsa-mir-3152-3p ; hsa-mir-6867-5p ; hsa-mir-3182 ; hsa-mir-1237-3p ; hsa-mir-92a-2-5p ; hsa-mir-2053 ; hsa-mir-6857-5p ; hsa-mir-4450 ; hsa-mir-8089 ; hsa-mir-4700-5p ; hsa-mir-4667-5p ; hsa-mir-6768-3p ; hsa-mir-4753-5p ; hsa-mir-1277-5p ; hsa-mir-3942-3p ; hsa-mir-5100 ; hsa-mir-190a-3p ; hsa-mir-892c-5p ; hsa-mir-5011-5p ; hsa-mir-5003-3p ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-511-5p ; hsa-mir-6830-3p ; hsa-mir-29a-5p ; hsa-mir-3920 ; hsa-mir-622 ; hsa-mir-4444 ; hsa-mir-4711-3p ; hsa-mir-4724-3p ; hsa-mir-501-5p ; hsa-mir-6782-3p ; hsa-mir-500b-5p ; hsa-mir-362-5p ; hsa-mir-2681-5p ; hsa-mir-421 ; hsa-mir-1245b-3p ; hsa-mir-3620-3p ; hsa-mir-6865-3p ; hsa-mir-4709-5p ; hsa-mir-3613-3p ; hsa-mir-548p ; hsa-mir-181c-3p ; hsa-mir-5683 ; hsa-mir-548c-3p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-378a-5p ; hsa-mir-7111-3p ; hsa-mir-6131 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-4680-5p ; hsa-mir-4635 ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-1273a ; hsa-mir-1273g-3p ; hsa-mir-3672 ; hsa-mir-4486 ; hsa-mir-4649-5p ; hsa-mir-4793-3p ; hsa-mir-4797-5p ; hsa-mir-508-5p ; hsa-mir-5586-3p ; hsa-mir-661 ; hsa-mir-6729-5p ; hsa-mir-6864-3p ; hsa-mir-759 ; hsa-mir-7703 ; hsa-mir-873-3p ; hsa-mir-939-3p

Nearest miRNA

hsa-mir-101-1/Upstream/647940; hsa-mir-1182/Downstream/134010;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/69295, chr1-CpG: 79/Downstream/94803

Upstream sequence

cacagcttctaagcaatagaattaggcttctggttcatgcctgttattccatcacagagcccccctcactccaaactttctGCAGAAAGTTGTTCAGCTC

Downstream sequence

TATCTACCAGGTATTGTCTCCCTACTACATCCCCATCCCCGAATGAGAGCACCTGCAGACATCTTTGCTTGCTAGCAGGAGTAAGGATGAGATGTGCGAG