Basic Information
VIS ID
TVIS10013829
Fusion event
HBV-chr1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|precore/core protein|
Start
1828
Orient
+
Integrated sequence
AGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTC| |ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATT
Host Sequence
Chromosome
chr1
Cytoband
q24.1
Reference genome
End
166688619/166719382 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/564584; hsa-mir-1182/Downstream/1279278;
Nearby gene
FMO9P(-94146) ; POGK(+120105) ;
Upstream sequence
ttcgggacttctggcttcttatggtttcgctaaagttttaggttactaaggatcagaattctagttaataggtaattctgtatacaaaatgtgtcagaaa
Downstream sequence
gtgttgtgttattagtgagaaaaagaatacttttgcctaactgagtagttatctaaaagttagttcaaattacagatttgaaaaggttatttttgaaaca
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate