Basic Information
VIS ID
TVIS10013833
Fusion event
HBV-LOC105372898 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
X protein|
Start
1750
Orient
-
Integrated sequence
CTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAG| |GAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTG
Host Sequence
Chromosome
chr1
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
209700321/209526976 (Hg38)
End
209700321/209526976 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105372898
Nearest miRNA
hsa-mir-101-1/Upstream/94734; hsa-mir-1182/Downstream/96468;
Nearest TSS
ENST00000473358/Upstream/154921; ENST00000423146/Downstream/20604;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/294848, chr1-CpG: 16/Downstream/98828
Nearby gene
MIR205HG(-94429) ; CAMK1G(+56724) ;
Upstream sequence
TTTCTACATGCCTTAAAATCTTATCATTTTAAACTCTAATTACTAGTACTAATTGGCTTTCATCTCTTAAGAGCCTATTTTATGCCAGGTACTATGCAAG
Downstream sequence
ATCCTCAAGGTACGTTTTCTTACTTATTATTTGTGATGGTAGCGATGTtagtaaagttagctcttactgagtccttaactatgccctgctctgagtcctc
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
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