VISDB Viral Integration Site DataBase

VIS ID

TVIS10013835

Fusion event

HBV-CLSPN integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2222

Orient

+

Integrated sequence

TTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTG| |TCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTA

Chromosome

chr1

Cytoband

p34.3

Reference genome

Start

End

36196800/35731199 (Hg38)

Orient

+

Location type

downstream

Target gene

miRNAs that regulate target gene

hsa-mir-148b-3p ; hsa-mir-128-3p ; hsa-mir-122-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-423-5p ; hsa-mir-615-3p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-4668-5p ; hsa-mir-7855-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-7106-5p ; hsa-mir-149-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-1827 ; hsa-mir-4537 ; hsa-mir-5186 ; hsa-mir-3192-5p ; hsa-mir-4756-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-7851-3p ; hsa-mir-490-3p ; hsa-mir-4503 ; hsa-mir-4477a ; hsa-mir-6792-5p ; hsa-mir-545-3p ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-548p ; hsa-mir-4760-3p ; hsa-mir-1303 ; hsa-mir-3149 ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-6504-5p ; hsa-mir-3064-5p ; hsa-mir-29a-5p ; hsa-mir-483-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3613-3p ; hsa-mir-5096 ; hsa-mir-4259 ; hsa-mir-4425 ; hsa-mir-450b-3p ; hsa-mir-5089-5p ; hsa-mir-571 ; hsa-mir-6513-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p

Nearest miRNA

hsa-mir-12136/Upstream/1061505; hsa-mir-101-1/Downstream/1430364;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/12014, chr1-CpG: 82/Downstream/38124

Upstream sequence

tggggcaggagaatcgcctgaacccgggaggcagaggttgcagtgagccgagatcgtaccactgcattccagcctgggcgacagggcgagactctgtctc

Downstream sequence

aaaaaaaaaaaaaagaaagaaagaaaaaaGAAAGGGGTGTTAATggtcagagaaggcttctctgaggaaattaggcttaagctaacaccttgagaattat