VISDB Viral Integration Site DataBase

VIS ID

TVIS10013837

Fusion event

HBV-chr1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1771

Orient

-

Integrated sequence

ACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTT| |GTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGC

Chromosome

chr1

Cytoband

p34.3

Reference genome

Start

End

36391299/35925698 (Hg38)

Orient

+

Location type

Intronic

Target gene

AGO1 ; AGO3

miRNAs that regulate target gene

hsa-mir-503-5p ; hsa-mir-129-5p ; hsa-let-7b-5p ; hsa-mir-148b-3p ; hsa-mir-130b-3p ; hsa-mir-106b-5p ; hsa-mir-107 ; hsa-mir-107 ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-320c ; hsa-mir-877-3p ; hsa-mir-877-5p ; hsa-mir-744-5p ; hsa-mir-455-3p ; hsa-mir-151a-5p ; hsa-mir-93-3p ; hsa-mir-769-3p ; hsa-mir-421 ; hsa-mir-652-3p ; hsa-mir-628-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-193b-3p ; hsa-mir-146b-5p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-324-5p ; hsa-mir-326 ; hsa-mir-328-3p ; hsa-mir-330-3p ; hsa-mir-378a-3p ; hsa-mir-320a ; hsa-mir-195-5p ; hsa-mir-194-5p ; hsa-mir-186-5p ; hsa-mir-185-5p ; hsa-mir-149-5p ; hsa-mir-138-5p ; hsa-let-7g-5p ; hsa-mir-212-3p ; hsa-mir-34a-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-197-3p ; hsa-mir-106a-5p ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-31-5p ; hsa-mir-29a-3p ; hsa-mir-26a-5p ; hsa-mir-25-3p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-let-7e-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-3678-3p ; hsa-mir-4779 ; hsa-mir-2467-3p ; hsa-mir-19a-3p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-103a-3p ; hsa-let-7d-5p ; hsa-let-7f-5p ; hsa-let-7i-5p ; hsa-mir-1-3p ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-4684-5p ; hsa-mir-4721 ; hsa-mir-3616-3p ; hsa-mir-942-5p ; hsa-mir-1251-5p ; hsa-mir-517-5p ; hsa-mir-325 ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-4632-5p ; hsa-mir-6735-5p ; hsa-mir-4436b-3p ; hsa-mir-100-3p ; hsa-mir-1273e ; hsa-mir-4722-5p ; hsa-mir-6087 ; hsa-mir-4740-3p ; hsa-mir-1827 ; hsa-mir-4768-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-302f ; hsa-mir-3166 ; hsa-mir-4756-3p ; hsa-mir-1324 ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-5089-5p ; hsa-mir-6878-3p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-6807-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-7106-3p ; hsa-mir-4312 ; hsa-mir-6778-3p ; hsa-mir-4252 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-212-5p ; hsa-mir-186-3p ; hsa-mir-1273g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-20b-5p ; hsa-mir-106a-5p ; hsa-mir-519d-3p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-6866-5p ; hsa-mir-877-5p ; hsa-mir-5689 ; hsa-mir-4795-3p ; hsa-mir-4528 ; hsa-mir-126-5p ; hsa-mir-382-3p ; hsa-mir-624-3p ; hsa-mir-410-3p ; hsa-mir-103a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-548aw ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1825 ; hsa-mir-8063 ; hsa-mir-4698 ; hsa-mir-551b-5p ; hsa-mir-548c-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-219b-3p ; hsa-mir-8075 ; hsa-mir-219a-2-3p ; hsa-mir-218-5p ; hsa-mir-3941 ; hsa-mir-7113-3p ; hsa-mir-6752-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4789-5p ; hsa-mir-6887-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-2115-5p ; hsa-mir-1178-3p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-4680-5p ; hsa-mir-767-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-1306-5p ; hsa-mir-4686 ; hsa-mir-6828-3p ; hsa-mir-378a-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-4266 ; hsa-mir-4717-5p ; hsa-mir-3919 ; hsa-mir-4695-5p ; hsa-mir-6510-5p ; hsa-mir-4690-5p ; hsa-mir-6165 ; hsa-mir-6793-3p ; hsa-mir-5003-3p ; hsa-mir-3180-5p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-660-3p ; hsa-mir-106a-3p ; hsa-mir-4634 ; hsa-mir-652-3p ; hsa-mir-454-3p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-539-3p ; hsa-mir-485-3p ; hsa-mir-5007-3p ; hsa-mir-323a-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-640 ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-6513-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-4279 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1976 ; hsa-mir-4485-5p ; hsa-mir-6890-3p ; hsa-mir-8055 ; hsa-mir-6864-3p ; hsa-mir-4715-3p ; hsa-mir-3672 ; hsa-mir-4727-5p ; hsa-mir-6868-3p ; hsa-mir-6794-3p ; hsa-mir-4294 ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-1304-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-4639-3p ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-1295a ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-6847-3p ; hsa-mir-4746-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-383-3p ; hsa-mir-4635 ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-4279 ; hsa-mir-4777-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-892b ; hsa-mir-122-5p ; hsa-mir-143-5p ; hsa-mir-3135b ; hsa-mir-3652 ; hsa-mir-4430 ; hsa-mir-455-3p ; hsa-mir-504-3p ; hsa-mir-4514 ; hsa-mir-4524b-3p ; hsa-mir-4692

Nearest miRNA

hsa-mir-12136/Upstream/1256004; hsa-mir-101-1/Downstream/1235865;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/41629, chr1-CpG: 131/Downstream/4950

Nearby gene

AGO1(-1400) ; AGO3(+5384) ;

Upstream sequence

TAGTCTGTGGTTTATGAGTATGGGCTGGGTGGGCAGTGGATCAAGAAGTGATAGGAGTACACAGGATGAACTCAGAATTCCTGAATCTTCAGGTAAGCAG

Downstream sequence

ATACTTAACTACATTATCATTGTCTTTTCCCACTCACCCCAAGTTGGAGGTTCTATGGTTTTGTACTTTAAGCTGGTGGTATAATTGTCAAGCATGTAAA