VISDB Viral Integration Site DataBase

VIS ID

TVIS10013839

Fusion event

HBV-CAMTA1 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|

Start

2143

Orient

-

Integrated sequence

TGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGT| |CTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAAC

Chromosome

chr1

Cytoband

p36.23

Reference genome

Start

End

7489364/7429304 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-129-5p ; hsa-mir-155-5p ; hsa-mir-218-5p ; hsa-mir-34a-5p ; hsa-mir-96-5p ; hsa-mir-124-3p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p

Nearest miRNA

hsa-mir-12136/Upstream/999408; hsa-mir-101-1/Downstream/1437198;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/366637, chr1-CpG: 111/Downstream/234036

Nearest cancer related gene

CAMTA1(TSG, No orient, 0)

Upstream sequence

ctggatacacaattggatacacgtacctcatatggtggttgcgaggttgaaatgtaatgatttatgtcaagcccttagcatagtgcacggcatattttaa

Downstream sequence

gtgttcaacacatggaaactATTCGCatggtgatgatggtgatgaggatggagataatgatgggcataatggtggtgatgatgatggtgataactatggt