VISDB Viral Integration Site DataBase

VIS ID

TVIS10013840

Fusion event

HBV-ZZZ3 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2407

Orient

+

Integrated sequence

AATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTC| |AATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTG

Chromosome

chr1

Cytoband

p31.1

Reference genome

Start

End

78039348/77573663 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-548aw ; hsa-mir-6071 ; hsa-mir-6828-3p ; hsa-mir-7158-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-3182 ; hsa-mir-767-3p ; hsa-mir-5688 ; hsa-mir-495-3p

Nearest miRNA

hsa-mir-101-1/Upstream/513461; hsa-mir-11399/Downstream/7560131;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/291124, chr1-CpG: 94/Downstream/108869

Upstream sequence

aagtttaaataaatatttctcagatgTACAATTCTAATAATCACAAAGTATGAAATTATACACAAATGCTGTTTAAAACACAGCAATGATAGTAGTCATT

Downstream sequence

TTTCAAAAGACAAGTTTAAAAGGAAATTTTAAAATTTTTATGAATACAGTTATTAAGGTAGTTTGATGCCAAAGTATACAATCAGTATTCGATTAATCTA