VISDB Viral Integration Site DataBase

VIS ID

TVIS10013843

Fusion event

HBV-JMJD1C integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2391

Orient

+

Integrated sequence

AGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCT| |CGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGG

Chromosome

chr10

Cytoband

q21.3

Reference genome

Start

End

65044998/63285238 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-326 ; hsa-let-7e-5p ; hsa-mir-374a-5p ; hsa-mir-718 ; hsa-mir-587 ; hsa-mir-6084 ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-145-3p ; hsa-mir-6880-3p ; hsa-mir-4485-5p ; hsa-mir-2681-5p ; hsa-mir-5579-3p ; hsa-mir-889-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-590-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-23c ; hsa-mir-130a-5p ; hsa-mir-23a-3p ; hsa-mir-23b-3p ; hsa-mir-8081 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-627-3p ; hsa-mir-205-5p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-6875-3p ; hsa-mir-670-3p ; hsa-mir-4762-5p ; hsa-mir-513b-3p ; hsa-mir-3662

Nearest miRNA

hsa-mir-1265/Upstream/5980679; hsa-mir-107/Downstream/87719;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/151662, chr10-CpG: 122/Downstream/179872

Upstream sequence

aatgtcgagttatctcataggtataatggagccccaaactgcaagtcatgtagcacgcacgacagaaaaagcattaatgacttaacaacacctggaacca

Downstream sequence

ataattcctctcctcagaacccagactgggacaggagcagaacctgaatgtcagaacctcttttggaagtgaggggtccattggccggaaaagatacagg