Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013846
Fusion event
HBV-KIRREL3 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1745
Orient
-
Integrated sequence
AAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGG| |GGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATC
Host Sequence
Chromosome
chr11
Cytoband
q24.2
Reference genome
End
126513485/126643590 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-let-7a-2/Upstream/3262078; hsa-mir-3167/Downstream/344868;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/226615, chr11-CpG: 27/Downstream/356740
Upstream sequence
ATGGTTCAGGGAAAGGTGACTAGTGGGAAATAGGACTGAAGATGTAGGCTGAGGCGATATCATGGCAAATCTTTATCTCTACACTGATGATATAGACTTG
Downstream sequence
ATCCTTGGGCAAAAGTGCATTAGTAGGGATTCTGGAGCAAGGCATAACtgtggtttaggaagatcaatgtggcaacacaatgagtaggattgtactgaag
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.