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VISDB
Viral Integration Site DataBase
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TVIS10013856
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013856
Fusion event
HBV-CTDSP2 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
30271481
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
Polymerase|
Start
2612
Orient
+
Integrated sequence
GTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTA| |ATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGA
Host Sequence
Chromosome
chr12
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
58239701/57845918 (Hg38)
End
58239701/57845918 (Hg38)
Orient
-
Location type
Intronic
Target gene
CTDSP2
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-193b-3p
;
hsa-mir-335-5p
;
hsa-mir-375
;
hsa-mir-24-3p
;
hsa-mir-615-3p
;
hsa-mir-106b-5p
;
hsa-mir-191-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-6797-5p
;
hsa-mir-1249-5p
;
hsa-mir-765
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4419a
;
hsa-mir-4510
;
hsa-mir-6840-3p
;
hsa-mir-665
;
hsa-mir-4459
;
hsa-mir-4756-5p
;
hsa-mir-4739
;
hsa-mir-1321
;
hsa-mir-4779
;
hsa-mir-1207-5p
;
hsa-mir-152-5p
;
hsa-mir-3192-3p
;
hsa-mir-4502
;
hsa-mir-4514
;
hsa-mir-4692
;
hsa-mir-4762-3p
;
hsa-mir-4763-3p
;
hsa-mir-6721-5p
;
hsa-mir-6808-5p
;
hsa-mir-6823-5p
;
hsa-mir-6871-5p
;
hsa-mir-6893-5p
;
hsa-mir-940
Nearest miRNA
hsa-mir-1228/Upstream/21226; hsa-let-7i/Downstream/4414441;
Nearest TSS
ENST00000382841/Upstream/384;
ENST00000619560/Downstream/626;
Nearest CpG islands
chr12-CpG: 151/Target
, None/Upstream, None/Downstream
Upstream sequence
CCACCGCGACCGCCCCCGCCTCCAAGAGGTGAACTTGGTCCCAAGTCCCGCCGGACGCCGTCACCGCCAGCTAGCTGCCCGAACGACCTCGGGCTTGGGG
Downstream sequence
GGGCCTGCAAGTGCTGGACTCCAGTCTCGGTTCCGTTCCACCTGGGGCTCCCTCTGTCACCTTCCTAACCCCTCCCCGCGATCCCGGGGCAGCCGCGCGC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Sample Information
×
Sample name
831P
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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