VISDB Viral Integration Site DataBase

VIS ID

TVIS10013871

Fusion event

HBV-DENND4A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1731

Orient

-

Integrated sequence

ACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGA| |CTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACC

Chromosome

chr15

Cytoband

q22.31

Reference genome

Start

End

66083095/65790757 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-92b-3p ; hsa-mir-25-3p

Nearest miRNA

hsa-mir-10393/Upstream/71425; hsa-mir-11181/Downstream/249476;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/179425, chr15-CpG: 104/Downstream/744

Upstream sequence

ATGTTTAATTCTGCCCAAAACAGTTTCCAAAAAAGAAGCCaaatataatattttattttaaGTTCAAACAGGGTTCAAACAGCTCAGAAATTTTGTATAC

Downstream sequence

TTAAGTTTTCAGAAGTCGAATCCCAGAACCGCTATCAACATAAACTGAATAACTTGCTCAAGAGTCCTTACTTATTACCCAATCTTAGGTCCCCCAGAAT