VISDB Viral Integration Site DataBase

VIS ID

TVIS10013890

Fusion event

HBV-TRAPPC6A integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

S protein|Polymerase|large S protein|middle S protein|

Start

226

Orient

+

Integrated sequence

TTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAA| |GAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAAC

Chromosome

chr19

Cytoband

q13.32

Reference genome

Start

End

45677735/45174477 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-3692-3p ; hsa-mir-10b-3p ; hsa-mir-4461 ; hsa-mir-8485

Nearest miRNA

hsa-mir-10395/Upstream/415756; hsa-let-7e/Downstream/262177;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/20622, chr19-CpG: 151/Downstream/3588

Upstream sequence

GCattcacctcctcaacacgtccacactgaggacccactacgagccaggacatccagtggtcatcaatacacacccaggcccatcccgcacaaagtacac

Downstream sequence

tccggctgggggagacgcatgtgaattaaaggatcatacagatacacaattcagacgcatcctggcagggcgtgctggctcacacctgtaatcccaggtg