Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013898
Fusion event
HBV-ARMC9 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1799
Orient
-
Integrated sequence
GAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGG| |TCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGG
Host Sequence
Chromosome
chr2
Cytoband
q37.1
Reference genome
End
232094174/231229461 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10b/Upstream/3757274; hsa-mir-1244-1/Downstream/133247;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/30559, chr2-CpG: 18/Downstream/20346
Upstream sequence
GATAGGAAGTTTTCACGGTTAAGTGAGATTACCAGAAGCTTTTAAAGAAGACAGGAAAGGCACTTGCAGCAGAAACTTCTCTCAGAAGGAATTACGTTTG
Downstream sequence
AAATGCTGTGTGGAATAAAAACAGGTTGACAATGTAGTAACATCGGATTATTATTTTCACCTAGTCACTTAAAAAGGATATAGAAATAGTATCTTTTGGC
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.