VISDB Viral Integration Site DataBase

VIS ID

TVIS10013903

Fusion event

HBV-KIF16B integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

precore/core protein|Core and e antigen|Polymerase|

Start

2381

Orient

+

Integrated sequence

GCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAAC| |TCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAA

Chromosome

chr20

Cytoband

p12.1

Reference genome

Start

End

16401388/16420743 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-7-5p ; hsa-mir-221-3p

Nearest miRNA

hsa-mir-103a-2/Upstream/5771048; hsa-mir-1-1/Downstream/2049872;

Nearest TSS

Nearest CpG islands

None/Target, chr20-CpG: 39/Upstream/2424321, chr20-CpG: 50/Downstream/152448

Upstream sequence

TTGACATCTTTTACTTCTATAAAAGGAAAATGCTGCTTGGGTCTGCCTCAAAAGgtttgtttgtttgtttgtttgtttTTTGATCTAATCAATGGGCCAA

Downstream sequence

ATACAGTGAGGTCCATTCTGAGGACCAAGACACAATGAGTCAGGAAGGGTCCTAGGCCAATAACCACTCCAATTAACCAGAAACTGGGATGAGGACAGTA