VISDB Viral Integration Site DataBase

VIS ID

TVIS10013906

Fusion event

HBV-FTCD integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|

Start

1793

Orient

-

Integrated sequence

GACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATA| |AATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGG

Chromosome

chr21

Cytoband

q22.3

Reference genome

Start

End

47570830/46150916 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-193b-5p ; hsa-mir-7155-5p ; hsa-mir-1976 ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-668-3p ; hsa-mir-483-3p

Nearest miRNA

hsa-let-7c/Upstream/672590;

Nearest TSS

Nearest CpG islands

None/Target, chr21-CpG: 261/Upstream/4485, chr21-CpG: 153/Downstream/9662

Upstream sequence

ATGCTGAGGGGTGGGGCCCCAGGCACCCCCATGCCGTTCTCCCATCCCATCTGCTCCGCTCCCGACAAGTCCCCTCAGCCCCGCACTTGTCGGGGTGACT

Downstream sequence

GAGTCCACGTGGGGGGACTCTGACCTCTGCCCTTGGCCGGGGCCTAAAGCAGGACTTAGAGGTCCCTGTGCTTTTGTGCTGAGTCTGCAGGTCGGGAAGC