Basic Information
VIS ID
TVIS10013910
Fusion event
HBV-LOC105374191 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
Polymerase|
Start
2487
Orient
-
Integrated sequence
GCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTAC| |TGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAA
Host Sequence
Chromosome
chr3
Cytoband
q26.1
Reference genome
End
164253631/164535843 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7g/Upstream/364287; hsa-mir-1224/Downstream/4016011;
Nearby gene
LINC01192(-1232542) ; SI(+443055) ;
Upstream sequence
gactaactcctcatctacttcaaatctttgctcaaatgtcaccctcttaatgagatctgctgtaactatttaaaactaccacacccaggccaggcgcggc
Downstream sequence
CTTTTGTGGCATAAAAGAAGTGGGGTTTCAATCATACAAATGAATGAGTAAATGTCAAACTAGAAAGGTAAAACCTTTATCTGAGTCAATTGCACAGTGT
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.
Curate