VISDB Viral Integration Site DataBase

VIS ID

TVIS10013920

Fusion event

HBV-ANK2 integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

X protein|precore/core protein|

Start

1820

Orient

-

Integrated sequence

TTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTAT

Chromosome

chr4

Cytoband

q25

Reference genome

Start

End

113903523/112982367 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-122-5p ; hsa-mir-335-5p ; hsa-mir-877-3p ; hsa-mir-647

Nearest miRNA

hsa-mir-12113/Upstream/333810; hsa-mir-1243/Downstream/124496;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/276016, chr4-CpG: 86/Downstream/778546

Upstream sequence

aggtaattgaatcaggggatgggtctttcccatgctgttctcgtgacagtgaataagcctcatgagatctgatagtttatttatttatttatttttgata

Downstream sequence

AAAGGCGGAGTAATGTAATCTGTATGAAGAATATGAATTTAGCCAATTCTGAACATCCACTCGGTAGCATAAGCAGATAATTGTTCTCAACAAATGAAAC