Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10013944
Fusion event
HBV-PHACTR1 integration
Validated
No
Detection method
NGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
X protein|
Start
1803
Orient
+
Integrated sequence
CATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTG| |CGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCA
Host Sequence
Chromosome
chr6
Cytoband
p24.1
Reference genome
Start
End
13140935/13140703 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-3691/Upstream/2700909; hsa-mir-10398/Downstream/3000853;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/125732, chr6-CpG: 41/Downstream/187652
Upstream sequence
ccatttgaattacagattagtttgcattttctggaatttatacaagtcaaatcacacagtttatattcttttgtctggtttctttccttccacacaatga
Downstream sequence
atggttgcacaatgatgtgaatctatttaacactgctgaactgtgcacttataaatggttaagatgataaattttcttatttatagtctaccaaaatgtt
Reference
Yang, L., et al. Molecular Characterization of HBV DNA Integration in Patients with Hepatitis and Hepatocellular Carcinoma. J Cancer ,2018,9(18): 3225-3235.