VISDB Viral Integration Site DataBase

VIS ID

TVIS10013951

Fusion event

HBV-MANEA integration

Validated

No

Detection method

NGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Region type

Polymerase|

Start

1161

Orient

-

Integrated sequence

TTGTATGCATGTATTCAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATACCTGAACCTTTACCCCGTTGCCCGGC| |AACGGCCAGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCT

Chromosome

chr6

Cytoband

q16.1

Reference genome

Start

End

96025181/95577305 (Hg38)

Orient

+

Location type

upstream

Target gene

miRNAs that regulate target gene

hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-1468-3p ; hsa-mir-545-3p ; hsa-mir-205-3p ; hsa-mir-4461 ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-548p ; hsa-mir-6859-5p ; hsa-mir-3125 ; hsa-mir-3916 ; hsa-mir-3120-3p

Nearest miRNA

hsa-mir-10398/Upstream/4055568; hsa-mir-1202/Downstream/2447226;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/2157346, chr6-CpG: 69/Downstream/60

Upstream sequence

GAGATCAGGCACGACCTCCTATGGGTGTTCACAGGAGATGGTGCCATGCATATGCAGAACTTCCAGGCTGGCATCTTCCACATCAGACCCACTGAGTGAG

Downstream sequence

CAGAAATAGGGCGGGAGTGCAGTCTGACTCCAATCCACACGTCCTTCCCCTCTGACAGAACGCCCCAAAACGCAGTCCTCTCTTTCTTCCGCGCCGCTCC